Research advances on the mechanism of mesenchymal stem cells in the treatment of acute kidney injury

Zhao Lan; Wang Me-xia

doi:10.3969/j.issn.1671-2390.y20-165

Journal of Clinical Nephrology > 2021 > 21(6): 521-526. > DOI: 10.3969/j.issn.1671-2390.y20-165

Zhao Lan, Wang Me-xia. Research advances on the mechanism of mesenchymal stem cells in the treatment of acute kidney injury[J]. Journal of Clinical Nephrology, 2021, 21(6): 521-526. DOI: 10.3969/j.issn.1671-2390.y20-165

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Research advances on the mechanism of mesenchymal stem cells in the treatment of acute kidney injury

Zhao Lan¹,
Wang Me-xia^2, ,

1. First Medical College, Shanxi Medical University, Taiyuan 030001, China;
2. Department of Critical care Medicine, first hospital, Shamxi Medical University, Taiyuan 030001, China

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Received Date: August 13, 2020
Available Online: May 11, 2023
Published Date: June 27, 2021

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Abstract

Abstract

Acute kidney injury(AKI)is a common clinical complication with a complex etiology and a poor prognosis.Although significant advances have been achieved in renal supportive therapy,the prevalence and mortality of AKI remain consistently elevated.As a novel type of cell extensively examined in regenerative medicine,mesenchymal stem cell(MSC)has the unique characteristics of wide availability,self-renewal and immune regulation.Many studies have confirmed that MSC could improve renal injury through a variety of mechanisms in AKI model.This review summarized the latest researches on MSC in the treatment of AKI.
- Acute kidney injury,
- Mesenchymal stem cell,
- Therapy

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References

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