Applications and prospects of single-cell RNA sequencing for renal disease researches

Wang Meng-jie; Dong Wei; Liang Xin-ling

doi:10.3969/j.issn.1671-2390.y20-118

Journal of Clinical Nephrology > 2021 > 21(8): 681-684. > DOI: 10.3969/j.issn.1671-2390.y20-118

Wang Meng-jie, Dong Wei, Liang Xin-ling. Applications and prospects of single-cell RNA sequencing for renal disease researches[J]. Journal of Clinical Nephrology, 2021, 21(8): 681-684. DOI: 10.3969/j.issn.1671-2390.y20-118

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Applications and prospects of single-cell RNA sequencing for renal disease researches

1. Division of Nephrology, Guangdong Provincial People's Hospital; Guangdong Academy of Medical Sciences, Guangzhou 510080, China;
2. School of Medicine, South China University of Technology, Guangzhou 510006, China

Funds:

National Natural Science Foundation of China(81770667)

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Received Date: June 18, 2020
Available Online: May 11, 2023
Published Date: August 27, 2021

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Abstract

Abstract

Single-cell RNA sequencing(scRNA-seq) technology is expanding our understanding of cellular mechanisms in the occurrence and development of renal diseases. This review described the latest advances of scRNA-seq technology, summarized the cellular atlas of healthy kidney and the discovery of renal-related diseases and proposed the current limitations and future prospects of scRNA-seq technology for renal diseases.
- Single-cell RNA sequencing,
- Renal disease,
- Application,
- Prospect

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