Liu Zi, Hu Zhi-juan. Applications of rituximab in the treatment of renal diseases[J]. Journal of Clinical Nephrology, 2021, 21(1): 78-82. DOI: 10.3969/j.issn.1671-2390.y19-211
    Citation: Liu Zi, Hu Zhi-juan. Applications of rituximab in the treatment of renal diseases[J]. Journal of Clinical Nephrology, 2021, 21(1): 78-82. DOI: 10.3969/j.issn.1671-2390.y19-211
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    Applications of rituximab in the treatment of renal diseases

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    • As a monoclonal antibody targeting CD20 on the surface of B lymphocytes,rituximab causes the dissolution of B cells through immune action.Plasma cells lack CD20 antigen.Rituximab is both effective and safe for lupus nephritis,ANCA-associated vasculitis,refractory minimal change nephropathy,focal segmental glomerulosclerosis and membranous nephropathy,but not for IgA nephropathy.This review summarized the applications of rituximab in the treatment of renal diseases.
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