Clinical significance of platelet related parameters in early diabetic nephropathic patients
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Abstract
Objective To evaluate the clinical significance of the changes in mean platelet volume(MPV),platelet-large cell ratio(P-LCR),platelet distribution width(PDW),neutrophil-lymphocyte ratio(NLR),platelet-lymphocyte ratio(PLR)and monocyte-lymphocyte ratio(MLR)in early diabetic nephropathy(DN).Methods Complete blood count(CBC)of 117 DN patients and 87 healthy controls(HC)were measured.Also PLR,NLR and MLR were compared among two groups.Results MPV,P-LCR,NLR,PLR and MLR were significantly higher in DN patients than those in HC group.Conclusion The levels of MPV,P-LCR,PDW,NLR,PLR and MLR become elevated in early DN patients.All these parameters have certain clinical reference values.
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