Research advances on novel therapeutic targets of microinflammatory response in chronic kidney disease

With rapid developments of science and society, public demands for physical health and higher quality-of-life are rising daily. In recent years, the occurrence and development of chronic kidney disease（CKD） has become a hot topic. CKD patients tend to have a mild, continuous and long-term inflammatory state leading to a gradual progression of disease. Currently there is no definite and unified therapeutic protocol for microinflammatory response of CKD. Based on recent experiments and clinical studies, this review summarized the latest advances of emerging therapeutic targets for modulating micro-inflammatory response pathway and arresting renal function decline to provide new clinical rationales for targeted treatment of microinflammatory response in CKD patients.