Epidemiological analysis of 84 mortal cases of maintenance hemodialysis at a single center

Objective To retrospectively analyze the epidemiology of mortal maintenance hemodialysis (MHD) patients in 2020 and provide rationales for improving the quality of life of hemodialysis.Methods For84 mortal MHD patients in 2020, the relevant clinical data were collected, including general status, original disease history, previous history, dialysis access, dialysis frequency, duration of dialysis and cause of mortality.Standard Operating Procedures of Blood Purification (2020 Edition) served as a reference standard.And the compliance status of the last biochemical results was recorded.The cohort was grouped by dialysis access, frequency of dialysis and pre-dialysis biochemical parameters.And dialysis survival between groups were compared.Results The mortality rate was13.3%.Most cases (n=47, 56.0%) occurred during February-April.Arteriovenous fistula (AVF) group was younger than the nonAVF group (median 61 vs 71 years);AVF group had longer dialysis time than non-AVF group (median 54 vs 30.5 months).The primary cause of mortality was chronic nephritis (29.8%), the most frequent previous history hypertension (83.3%), the primary cause of mortality infection (28.6%) and the highest frequency of dialysis thrice a week (60.0%).The compliance rates of the last biochemical parameters of hemoglobin (Hb), ferritin, albumin (Alb), calclum, phosphorus, potassium and iPTHpre-dialysis were 25%, 52.9%, 13.4%, 55.7%, 48.6%, 71.4%, 16.1%.The median survival time on dialysis was longer in AVF group than that in non-AVF group (54 vs 30.5 months), the median survival time on dialysis 5 times per 2 weeks longer than 3 times a week and twice a week (62.5 vs 47 vs 23.5 months), Ca<2.1mmol/L or >2.5mmol/L median survival time on dialysis greater than 2.1-2.5 mmol/L group (62 vs 30 months).Conclusion Chronic nephritis was the primary original disease of mortal hemodialysis patients in 2020 and infectiona leading cause of mortality.Patients with arteriovenous fistula as vascular accessand those with dialysis frequency of 5 times per 2 weeks had a longer survival time on dialysis.