Control nutritional status score and platelet/lymphocyte ratio relationship with left ventricular hypertrophy in peritoneal dialysispatients

Objective Using controlling nutritional status (CONUT) score and platelet to lymphocyte ratio (PLR),to evaluate the nutritional status and inflammation status of patients with peritoneal dialysis (PD),and analyze their relationship with left ventricular hypertrophy.Methods The patients undergoing peritoneal dialysis in Department of Nephrology,Affiliated Hospital of Xuzhou Medical University from January 2019 to May 2020 were enrolled.General patient information and laboratory indicators were collected.Cardiac color Doppler ultrasound was used to assess changes in the patient's cardiac structure.According to the presence or absence of left ventricular hypertrophy (LVH),the patients were divided into LVH group and non-LVH group.Each indicator was compared between the two groups,and risk factors of LVH were analyzed by logistic regression method.ROC curve was used to analyze the sensitivity and specificity of PLR and CONUT in diagnosing LVH.Results (1) A total of 82 patients were included,and the incidence of LVH was 40.2%.Systolic blood pressure,uric acid,PLR and CONUT scores of the LVH group were significantly higher than those of the non-LVH group; and Hb,LVEF and Alb were significantly lower than those of the non-LVH group (P<0.05),with statistical significance.(2) Logistic regression analysis showed that systolic blood pressure,PLR and CONUT score were all risk factors affecting left ventricular hypertrophy.(3) The areas under the curve of LVH ROC curve analysis found that,the areas under the curve of LVH PLR and CONUT score predicted in PD patients were 0.743 and 0.822,respectively,and the combined prediction value was 0.855.Conclusions CONUT score and PLR are associated with LVH in peritoneal dialysis patients,and are the influencing factors of LVH.The combination between CONUT score and PLR is more valuable in predicting LVH in PD patients.