Analysis on influencing factors of hemodialysis adequacy in maintenance hemodialysis patients

Objective To explore the influencing factors of adequacy of single hemodialysis in maintenance hemodialysis (MHD) patients.Methods A total of 109 patients who underwent MHD in Blood Purification Centre of Aviation General Hospital in March 2019 were enrolled in this study.The data on pre-HD and post-HD gender,age,body mass index (BMI),primary disease,vascular access and blood urea nitrogen (BUN),hemodialysis time,ultrafiltration volume (UF),blood flow rate (BFR),dry body weight and ratio of UF in single hemodialysis were recorded.According to spKt/v results,the patients were divided into two groups:qualification group (spKt/V ≥ 1.2) and disqualification group (spKt/v<1.2).The influencing factors were analyzed.Results Univariate analysis showed that spKt/V was correlated with gender,dialysis associated coagulation,BFR,arteriovenous fistula (AVF)and dry body weight (P<0.05).Binary Logistic regression showed that gender (OR=4.345,95%CI 1.240~15.070,P<0.05),dialysis associated coagulation (OR=5.497,95%CI 1.213~27.125,P<0.05),BFR(OR=0.984,95%CI 0.969~0.998,P<0.05) and AVF as vascular access (OR=0.105,95%CI 0.012~0.889,P<0.05) were independent influencing factors of spKt/V for single hemodialysis.Conclusions The single hemodialysis adequacy in MHD patients is closely associated to gender,dialysis associated coagulation,BFR and AVF.