Correlation analysis of pathogenic bacteria characteristics and serum calcitonin levels in peritoneal dialysis related peritonitis

Objective To analyze the correlation between the characteristics of pathogenic bacteria and the serum procalcitonin levels in peritoneal dialysis related peritonitis.Methods Select 138 cases peritoneal dialysis related peritonitis in the peritoneal dialysis center of Central Hospital of Shengli Oil Field, treated with peritoneal dialysis from January 2013 to December 2017, of which 97 cases were positive for peritoneal dialysis bacteria culture. According to the result of culture, it was divided into Gram-positive bacteria and Gram-negative bacteria groups. Comparison of the differences of hemoglobin, serum albumin, leukocyte, percentage of blood neutrophils, peritoneal leukocytes, peritoneal polykaryotes, c-reactive proteins, serum calcitonin, and the correlation with pathogenic bacteria between the two groups were compared.Results Peritoneal dialysis was associated with 97 cases (70.29%) of positive peritonitis peritoneal dialysis culture, including 51 cases (52.58%) of gram-positive bacteria (G⁺), mainly epidermococcal staphylococcus and vaustenococcusaureus. Gram negative bacterium (G^-) 46 cases (47.42%), mainly escherichia coli, enterobacter cloacae. Between the two groups in age, dialysis age, seasonality, hemoglobin, serum albumin, white blood cells, blood neutrophil percentage, peritoneal dialysate white blood cells, multinucleated cells and C reactive protein had no difference(P>0.05), There was a significant difference in serum calcitonin levels(P<0.01).Conclusions Peritoneal dialysis-related peritonitis was mainly caused by G⁺ bacteria infection. The detection of serum calcitonin can be used to distinguish G⁺ bacteria from G^- bacteria infection.