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CHENG Li, XIONG Fei, ZHANG Yan-min, WAN Sheng, MAO Dong-dong. Comparison of anemia in elderly patients with peritoneal dialysis and hemodialysis[J]. Journal of Clinical Nephrology, 2018, 18(8): 475-479. DOI: 10.3969/j.issn.1671-2390.2018.08.006
Citation: CHENG Li, XIONG Fei, ZHANG Yan-min, WAN Sheng, MAO Dong-dong. Comparison of anemia in elderly patients with peritoneal dialysis and hemodialysis[J]. Journal of Clinical Nephrology, 2018, 18(8): 475-479. DOI: 10.3969/j.issn.1671-2390.2018.08.006

Comparison of anemia in elderly patients with peritoneal dialysis and hemodialysis

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  • Received Date: December 28, 2017
  • Rev Recd Date: July 09, 2018
  • Available Online: May 11, 2023
  • Published Date: August 27, 2018
  • Objective The comparison of anaemia in elderly patients with peritoneal dialysis (PD) and hemodialysis (HD) provides evidence for clinical treatment of anemia.Methods The relevant data of elderly patients aged over 65 years in the peritoneal dialysis center and hemodialysis center of our hospital were collected and classified into 79 cases in the PD group and 152 cases in the HD group according to different dialysis methods. Cross-sectional analysis was conducted to compare the differences in anemia and related indicators in the two groups.Results The levels of Hemoglobin (Hb) and Serum ferritin (SF) in PD group and in HD group, the difference between the two groups was statistically significant (P<0.05). The results of comparison of Hb, CRP, SF and PTH in PD and HD groups showed that there was no significant difference in the older men (P>0.05). In elderly women, Hb and SF levels in PD group were significantly higher than HD group, the difference was statistically significant (P<0.05). When Hb>90 g/L,The SF level in PD group and the HD group, the difference was statistically significant (P<0.05). A binary logistic regression analysis of factors that may affect anemia in elderly dialysis patients concluded that residual renal function(RRF) is an independent risk factor for anemia in elderly dialysis patients.Conclusions Anemia occurs more frequently in elderly patients with PD and HD, and the difference is more significant in women. To some extent, there is a connection with RRF.
  • [1]
    Couchoud C, Lassalle M, Jacquelinet C. REIN Report 2011--summary[J]. Nephrol Ther, 2013, 9(Suppl 1):S3-S6.
    [2]
    Byrne C, Ford D, Gilg J, et al. UK Renal Registry 12th Annual Report (December 2009):chapter 3:UK ESRD incident rates in 2008:national and centre-specific analyses[J]. Nephron Clin Pract, 2010, 115(1):c9-c39.
    [3]
    刘书馨, 王丹, 刘红, 等. 老年血液透析和腹膜透析患者生存分析的单中心回顾性研究[J]. 中国中西医结合肾病杂志, 2016, 17(9):781-784.
    [4]
    Krairittichai U, Supaporn T, Aimpun P, et al. Anemia and survival in Thai hemodialysis patients:evidence from national registry data[J]. J Med Assoc Thai, 2006, 89(2):S242-S247.
    [5]
    Oliveira MC, Ammirati AL, Andreolli MC, et al. Anemia in patients undergoing ambulatory peritoneal dialysis:prevalence and associated factors[J]. J Bras Nefrol. 2016, 38(1):76-81.
    [6]
    The 2012 Kidney Disease:Improving Global Outcomes(KDIGO) Clinical Practice Guideline for Anemia in chronic Kidney Disease[M]. Kidney Int Suppl, 2012, 2:282.
    [7]
    Saran R, Li Y, Robinson B, et al. US Renal Data System 2014 Annual Data Report:Epidemiology of Kidney Disease in the United States[J]. Am J Kidney Dis, 2015, 66(Suppl 1):S1-S305.
    [8]
    陈香美, 孙雪峰. 共同参与有效防治老年肾脏病[J]. 中华医学信息导报, 2014, 29(5):14.
    [9]
    Farragher J, Rajan T, Chiu E, et al. Equivalent Fall Risk in Elderly Patients on Hemodialysis and Peritoneal Dialysis[J]. Perit Dial Int, 2016, 36(1):67-70.
    [10]
    Kim H, An JN, Kim DK, et al. Elderly Peritoneal Dialysis Compared with Elderly Hemodialysis Patients and Younger Peritoneal Dialysis Patients:Competing Risk Analysis of a Korean Prospective Cohort Study[J]. PLoS One, 2015, 10(6):e0131393.
    [11]
    Malavade T, Sokwala A, Jassal SV. Dialysis therapies in older patients with end-stage renal disease[J]. Clin Geriatr Med, 2013, 29(3):625-639.
    [12]
    Jin DC. Current status of dialysis therapy in Korea[J]. Korean J Intern Med, 2011, 26(2):123-131.
    [13]
    Rouveure AC, Bonnefoy M, Laville M. Conservative treatment, hemodialysis or peritoneal dialysis for elderly patients:The choice of treatment does not influence the survival[J]. Nephrol Ther, 2016, 12(1):32-37.
    [14]
    中国医师协会肾内科医师分会肾性贫血诊断和治疗共识专家组. 肾性贫血诊断与治疗中国专家共识(2014修订版)[J]. 中华肾脏病杂志, 2014, 30(9):712-715.
    [15]
    Ryta A, Chmielewski M, Debska-Slizien A, et al. Impact of gender and dialysis adequacy on anaemia in peritoneal dialysis[J]. Int Urol Nephrol, 2017, 49(5):903-908.
    [16]
    Eser B, Yayar O, Buyukbakkal M, et al. Fibroblast growth factor is associated to left ventricular mass index, anemia and low values of transferrin saturation[J]. Nefrologia, 2015, 35(5):465-472.
    [17]
    Portolés J, Gorriz JL, Rubio E, et al. The development of anemia is associated to poor prognosis in NKF/KDOQI stage 3 chronic kidney disease[J]. BMC Nephrol, 2013, 14:2.
    [18]
    Drüeke TB, Parfrey PS. Summary of the KDIGO guideline on anemia and comment:reading between the (guide)line(s)[J]. Kidney Int, 2012, 82(9):952-960.
    [19]
    Gilbertson DT, Ebben JP, Foley RN, et al. Hemoglobin level variability:associations with mortality[J]. Clin J Am Soc Nephrol, 2008, 3(1):133-138.
    [20]
    Ebben JP, Gilbertson DT, Foley RN, et al. Hemoglobin level variability:associations with comorbidity, intercurrent events, and hospitalizations[J]. Clin J Am Soc Nephrol, 2006, 1(6):1205-1210.
    [21]
    Wang WN, Zhang WL, Sun T, et al. Effect of peritoneal dialysis versus hemodialysis on renal anemia in renal in end-stage disease patients:a meta-analysis[J]. Ren Fail, 2017, 39(1):59-66.
    [22]
    Yotsueda R, Tanaka S, Taniguchi M, et al. Hemoglobin concentration and the risk of hemorrhagic and ischemic stroke in patients undergoing hemodialysis:the Q-cohort study[J]. Nephrol Dial Transplant, 2018, 33(5):856-864.
    [23]
    Kalantar-Zadeh K, Aronoff GR. Hemoglobin Variability in Anemia of Chronic Kidney Disease[J]. J Am Soc Nephrol, 2009, 20(3):479-487.
    [24]
    徐丽霞, 梁馨苓, 史伟. 维持性血液透析患者贫血:KIDGO指南解读[J]. 中国血液净化, 2014, 13(1):27-30.
    [25]
    Li H, Wang SX. Intravenous iron sucrose in peritoneal dialysis patients with renal anemia[J]. Perit Dial Int, 2008, 28(2):149-154.
    [26]
    Zeidan A, Bhandari S. Anemia in Peritoneal Dialysis Patients; Iron Repletion, Current and Future Therapies[J]. Perit Dial Int, 2017, 37(1):6-13.
    [27]
    Rozen-Zvi B, Gafter-Gvili A, Paul M, et al. Intravenous versus oral iron supplementation for the treatment of anemia in CKD:systematic review and meta-analysis[J]. Am J Kidney Dis, 2008, 52(5):897-906.
    [28]
    Roszkowska-Blaim M, Skrzypczyk P. Residual renal function in children treated with chronic peritoneal dialysis[J]. Scientific World Journal, 2013:154537.

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