The risk factors of multiple organ dysfunction syndrome caused by bee stings

Objective To explore the risk factors of multiple organ dysfunction syndrome (MODS) caused by bee stings.Methods The clinical data of 168 cases of bee sting patients in Bazhong Hospital from Jan. 2010 to Dec. 2015 were selected and the patients were divided into MODS group (12 cases) and non-MODS group (156 cases) according to the occurrence of MODS. General situation, the occurrence of MODS and auxiliary examination results in two groups were comparatively analyzed and the risk factors of MODS caused by bee sting injury were analyzed by Multi factor Logistic regression method.Results There was no significant difference in gender of patients between the two groups. The mortality rate of patients whose Sequential Organ Failure Assessment (SOFA) score > 10 was higher than that with SOFA score <10 and the difference was statistically significant (P<0.01). According to the following criteria for the demarcation of the basis and analysis:age >55 years, the duration from bee stings to hospitalization ≥ 6 h, white blood cell count (WBC) >20×10⁹/L, hemoglobin (Hb) <90 g/L, blood potassium (K⁺) >5.5 mmol/L, carbon dioxide combining power (CO₂-CP) >20 mmol/L, cardiac troponin I (cTnI) >0.7 μg/L, creatine kinase isoenzyme (CK-MB) >60 U/L, prothrombin time (PT) >15 s, blood urea nitrogen (BUN) >14 mmol/L and serum creatinine (SCr) >171 μmol/L were all independent risk factors of MODS in bee stings patients (P<0.05 or P<0.01).Conclusions Age, the duration from bee stings to hospitalization, WBC, Hb, serum K⁺, CO₂-CP, blood cTnI, CK-MB, PT, BUN, and SCr are all independent risk factors of MODS in bee stings patients.