Abstract: Cardiovascular disease is one of the leading causes of mortality in patients with chronic kidney disease (CKD). And arrhythmias is a predominant symptom. As compared with the general population, the etiology of arrhythmias is more complex and formulating appropriate treatment strategies have remained problematic. This review summarized common types, risk factors, pathophysiological mechanisms and current managements of arrhythmia in CKD patients, especially those with end-stage renal disease.