早期糖尿病肾病患者血小板相关参数测定的临床意义

姜国英; 陈德政; 张勇; 王明莉; 唐小琰; 彭李

doi:10.3969/j.issn.1671-2390.w20-192

早期糖尿病肾病患者血小板相关参数测定的临床意义

Clinical significance of platelet related parameters in early diabetic nephropathic patients

摘要

摘要: 目的探究早期糖尿病肾病患者（diabetic nephropathy，DN）平均血小板体积（mean platelet volume，MPV），大血小板比率（platelet-large cell ratio，P-LCR），血小板分布宽度（platelet distribution width，PDW），中性粒细胞/淋巴细胞比率（neutrophil/lymphocyte ratio，NLR），血小板/淋巴细胞比率（platelet/lymphocyte ratio，PLR）和单核细胞/淋巴细胞比率（monocyte/lymphocyte ratio，MLR）的临床意义。方法选取简阳市人民医院肾内科117例DN患者和健康体检中心的87名健康对照者进行全血细胞计数。同时，计算NLR，PLR和MLR用于组间比较。结果 DN患者MPV、P-LCR、PDW、NLR、PLR和MLR水平明显高于对照组，差异具有统计学意义。结论早期DN患者MPV、P-LCR、PDW、NLR、PLR和MLR均上升，具有一定的临床参考价值。

Abstract: Objective To evaluate the clinical significance of the changes in mean platelet volume(MPV),platelet-large cell ratio(P-LCR),platelet distribution width(PDW),neutrophil-lymphocyte ratio(NLR),platelet-lymphocyte ratio(PLR)and monocyte-lymphocyte ratio(MLR)in early diabetic nephropathy(DN).Methods Complete blood count(CBC)of 117 DN patients and 87 healthy controls(HC)were measured.Also PLR,NLR and MLR were compared among two groups.Results MPV,P-LCR,NLR,PLR and MLR were significantly higher in DN patients than those in HC group.Conclusion The levels of MPV,P-LCR,PDW,NLR,PLR and MLR become elevated in early DN patients.All these parameters have certain clinical reference values.

HTML全文

参考文献(29)

施引文献

资源附件(0)