Abstract:
Objective To explore the correlation between visceral obesity and chronic kidney disease(CKD)in adults in northern China.
Methods The database of Health and Nutrition of Chinese Residents in 2009 was searched.Finally 5,539 subjects were included for analysis.They were divided into four groups of normal waist triglyceride(TG)(A),high waist circumference(WC)(B),hypertriglyceride(C)and hypertriglyceride WC(D)according to WC≥90 cm in males and 85 cm in females and TG≥1.7 mmol/L.Based upon glomerular filtration rate(GFR),they were divided into CKD and non-CKD groups.Visceral fat index(VAI)and fat accumulation index(LAP)were calculated.And the correlationswere examined between triglyceride waist circumference,VAI,LAP and chronic kidney disease.
Results The age of D group was older and blood pressure,waist circumference,LDL-C,VAI,LAP and BMI were higher than other groups.Also proportion of female,smoking,alcoholism,myocardial infarction,hypertension,diabetes,CKD and urban population were higher than other groups(
P<0.05).The number of high TG WC phenotype in CKD group was higher than that in non-CKD group.Unconditioned Logistic regression analysis indicated that,after adjusting for age,gender,LDL-C,blood pressure,smoking,alcoholism,hypertension,diabetes,myocardial infarction and stroke history,OR value of D group was 1.35(0.98-1.87).The difference was statistically significant.
Conclusion Hypertriglyceride WC phenotype is an excellent predictor of CKD in healthy adults in northern China.However,VAI,LAP or BMI has no correlation with CKD.