Abstract: Objective To observe the application of improved fixation of peritoneal dialysis(PD) during PD catheterization.Methods From June 2014 to June 2019,a total of 120 end-stage renal disease patients on PD aged above 18 years were randomly divided into two groups of traditional and improved abdominal wall fixation(n=60 each).During a follow-up period of 6 months,catheter related complications were compared.Results No inter-group differences existed in gender,age,height,weight,body mass index,surface area,creatinine/urea level,glomerular filtration rate or albumin/hemoglobin level.None of them had an onset of abdominal visceral injury,bloody ascites,fluid leakage,surgical incision infection or poor healing.No inter-group differences existed in operative duration,incidence of peritonitis or hernia(P>0.05).The rates of catheter drift and greater omentum packaging were high in traditional group than those in abdominal wall fixation group(P<0.05).Conclusion Improved PD fixation may reduce the odds of PD catheter malfunction.