Abstract: Objective To explore the effects of electronic aids on dietary compliance and acid load in chronic kidney disease(CKD) patients.Methods A total of 116 patients with metabolic acidosis plus CKD3-4 at CKD management clinic were recruited and divided into two groups by single/double digit random method.Control group(n=49) received routine care and health tutorial according to CKD stages while research group(n=54) had additional electronic aids.Baseline demographics,medication usage,renal function,biochemistry,urinary protein,attitude/behavior score of dietary compliance and other indicators were collected and compared with those after 12-month intervention.Results A total of 103 patients completed follow-ups.No statistically significant inter-group difference in baseline clinical characteristics(P<0.05).The values of daily protein intake(DPI) and normalized protein equivalent of nitrogen appearance(nPNA) of research group were lower than baseline(P<0.05).After 12 months,the total score of attitude/behavior score of dietary compliance was higher in research group than control group.And the difference was statistically significant(P<0.05);potential renal acid load(PRAL) was lower(P<0.05) and blood total carbon dioxide(T-CO₂) significantly higher(P<0.05).Serum levels of creatinine and estimated glomerular filtration rate(eGFR) in research group had no significant change from baseline(P>0.05) and blood urea declined from baseline(P<0.05);serum levels of creatinine and urea increased in control group(P<0.05) and eGFR decreased from baseline(P<0.05).Conclusion The integration of electronic intelligent aids in the management of CKD patients can boost dietary compliance,improve metabolic acidosis and delay the decline of renal function.