继发性甲状旁腺功能亢进的发病机制和诊治
Pathogenesis and diagnosis of secondary hyperparathyroidism
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摘要: 继发性甲状旁腺功能亢进(secondary hyperparathyroidism,SHPT)是慢性肾脏病(chronic kidney disease,CKD)常见的并发症,大大增加了患者的病死率。但其发病机制复杂,疾病的不同时期采用的治疗手段亦不相同。本文将结合以往研究,对CKD患者并发SHPT的发病机制及诊治进行综述,为临床工作提供参考。Abstract: As a common complication of chronic kidney disease (CKD),secondary hyperparathyroidism (SHPT)greatly increases the mortality of patients.However,its underlying pathogenesis is rather complex and its treatments vary during different stages of disease.In conjunctions with previous studies,the pathogenesis,diagnosis and treatment of SHPT in CKD patients were reviewed for providing references for clinical practices.