Risk factor analysis of chronic kidney diseases using based on case control study
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摘要: 目的 基于病例对照研究慢性肾脏病（CKD）发病的危险因素。方法 搜集2017年1月至2018年6月期间于深圳市中医院确诊为CKD的患者243例作为CKD组，并用随机抽样的方法抽取于深圳市中医院体检的非肾脏病人群292例为对照组，通过对临床资料进行回顾性分析及问卷调查（主要内容为过去一年的生活状态），分析影响CKD发病的相关危险因素如基本情况、近一年感染情况、高血脂、高血压、糖尿病、高尿酸血症、心血管疾病、饮食习惯、运动习惯等。结果 两组人群性别、年龄段、高血脂、高血压、糖尿病、高尿酸血症、心血管疾病、近一年感染情况、饮食咸淡、饮用水类型、每日奶制品摄入量、睡眠质量比较，差异均具有统计学意义（P<0.05）；影响CKD发病的多因素回归分析：近一年感染情况（经常）、高血压、高尿酸血症、饮用水（桶装水）是发生CKD的独立危险因素，其OR（95%CI）分别为2.511（1.109~5.686）、3.825（2.167~6.751）、4.352（2.523~7.509）、1.676（1.026~2.737）。结论 早期发现影响CKD发病的危险因素，并积极及时给予综合防治，对于降低CKD发病率、规范CKD健康管理具有非常重要的意义。Abstract: Objective To study the risk factors of chronic kidney disease (chronic kidney disease,CKD) based on case-control study. Methods In the period from January 2017 to June 2018, 243 patients diagnosed with CKD were selected as the CKD group, and 292 patients with non-kidney disease, who were examined in Shenzhen TCM Hospital, were taken in a way of random sampling as the control group. Through the retrospective analysis of the clinical data and the questionnaire (the main content is the life state of the last year), the relevant risk factors that affect onset of CKD were analyzed, such as basic conditions, infection in the last year, hyperlipidemia, hypertension, diabetes, hyperuricemia,hyperuricemia, cardiovascular diseases. eating habits, sports habits,etc. Results There were significant differences in sex, age, hyperlipidemia, diabetes, hypertension, cardiovascular disease, infection,salty diet, drinking water type and daily dairy intake between the two groups (P<0.05). Multivariate regression analysis showed that the frequency of colds (frequent), hypertension, hyperuricemia and drinking water (bottled water) were the independent risk factors for CKD. Their ORs (95%CI) were 2.511 (1.109), 3.825 (2.167), 4.352 (2.523~7.509), 1.676 (1.026~2.737), respectively. Conclusions It is very important to early find the risk factors leading to onset of, and conduct comprehensive prevention and treatment actively, which are crucial for reducing incidence of CKD and standardizing health management of CKD.
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Keywords:
- Case-control study /
- Chronic kidney disease /
- Risk factors.
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