Abstract: Objective To observe the clinical effect of the constriction for tumor-like dilatation of internal arteriovenous fistula. Methods From January, 2016 to October, 2017, The patients hospitalized in Center for Blood Purification of Hainan Province People's Hospital from January, 2016 to October, 2017 were selected to conduct retrospective analysis on clinical features, surgery method, success rate, indications of surgical treatment, postoperative follow-up and internal fistula usein these patients.Results In 28 patients, with 16 males and 12 females, their average age was 47.0±12.2 years old, the average dialysis age was 73.8±33.7 months, and the time period from the construction of internal autogenous arteriovenous fistula development of tumor-like dilatation time was 51±22 months. In 23 cases, the catheter was used as the support to narrow the tumor like dilatation; in 3 cases, removal of tumor-like dilatation and proximal reconstruction were performed; and in 2 cases, ligation of arteriovenous fistula and opposite reconstructed were performed. The operation success rate was 100%. During postoperative follow-up of 6~12 months,clinical symptoms improved obviously, and the diameter of the arteriovenous fistula was reduced from (3.22±0.77)cm before operation to 1.49 ±0.26 cm after operation, with difference of statistical significance (t=13.686, P< 0.01). The blood flow rate in the brachial artery was decreased from the preoperative 2.9±0.9 L/min to the postoperative 1.3±0.4 L/min, and the difference was statistically significant(t=13.372, P< 0.01).The arteriovenous fistula was re-used 1~14 days after operation. Conclusions The effect of constriction for the treatment of arteriovenous fistula is significant.